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In this study, people who have signed up to the UK MS Register are asked to complete regular online questionnaires about their MS and how the coronavirus pandemic is affecting their life and MS.

Research has shown that the brain can compensate, adapt to damage and develop new connections that help people recover physical functions of the body such as arm or leg movement.

Dr Gallagher is testing a new magnetic resonance imaging (MRI) technique – called hyperpolarized carbon-13 MRI – to measure changes in the brains of people with MS.

Professor Barkhof and his team have identified a feature of MRI scans that could help them distinguish MS from other types of damage.

This project aims to determine whether systemic infections (such as colds, sinusitis and chest infections) can affect the accumulation of disability in people with MS.

This project aims to develop an imaging technique to detect early changes in acidity level in the brains of people with relapsing MS.

Our researchers are working to develop a blood test that can tell the difference between relapsing and progressive MS.

Our researchers want to develop a new way of measuring nerve damage.

Many people with MS find their symptoms get worse in the heat. Heat sensitivity can have a huge impact on day to day activities, and right now we don’t have a treatment that can help to manage it.

This project aims to identify if a technique called intermittent theta burst stimulation treatment improves cognition for people with MS.

In MS, the immune system damages the protective myelin coating around nerve cells. In order for the brain to repair the damage with new myelin, it first has to get rid of the old myelin debris.

Up to 80% of people with MS experience cognitive changes. These can include problems with memory and thinking, attention or multitasking. We want to develop a cognitive screening pathway to detect these changes.

Find out about research to make the assessment of treatments for people with MS more relevant to the condition.

In MS the protective myelin coating around nerve cells is damaged. Our bodies have the ability to repair myelin, but unfortunately in MS this process becomes less effective over time.

Exercise can reduce levels of fatigue for people with MS, as well as improving fitness and increasing general wellbeing. We're funding a trial to look for a safe and effective way of encouraging people with MS to make physical activity part of their everyday life.

Researchers are identifying people with MS who could benefit from cognitive rehabilitation and providing evidence to show its effectiveness.

In MS, our nerves are attacked by our own immune system. A variety of immune cells are involved, including a group called T cells. Scientists have discovered that the fatty layer around T cells is altered in MS, which could help to explain their altered behaviour

In MS the protective myelin coating around nerve cells is damaged and needs to be repaired by the body. As MS progresses, myelin repair becomes less efficient and damage accumulates, meaning that nerves don't function properly. A type of immune cell in the brain, called microglia, can produce proteins and other molecules that promote myelin repair, but how many of these ‘factors’ work is not yet known.

Progression in MS is strongly associated with age, and this innovative project will test the idea that cell ageing is responsible for progression of disability

We’re supporting a trial to find out if early intensive treatment is the best way to control accumulation of disability in relapsing MS.