Latest research news

Get up-to-date with everything MS research.

Our research community keep us updated with all the latest news. You can also head over to our research blog for a more in depth look at developments.

More real-world evidence on the effectiveness of HSCT

New real-world study suggests HSCT may be more effective at reducing relapses than two highly effective DMTs, but not at slowing disability worsening.

Connecting the puzzle pieces: the role of monocytes in myelin repair

Last week, an international group of scientists published new research, adding another piece to the myelin repair puzzle.

Behind the headlines: does eating fish reduce MS progression?

New research has found a link between a diet high in fish and a reduced risk of disability progression in MS. This tells us more about the role that diet could play in MS.

ChariotMS trial for advanced progressive MS completes recruitment

We're pleased to share that the 200th person with advanced progressive MS has joined the ChariotMS trial. The trial team have now reached their recruitment goal and we expect to have the first results in 2027.

New study sheds light on the safety of MS treatments during pregnancy

A large study of over 3700 pregnancies in people with MS has found that most treatments for MS don’t increase the risk of miscarriage, premature birth or major congenital anomalies.

Researchers create an ‘atlas of MS brain cells’ which could help personalise MS treatment

Researchers used information from post-mortem brain tissue to help understand how MS affects people differently.

Octopus trial reaches recruitment milestone

We’re pleased to share the news that our Octopus trial has recruited more than 375 people with MS to the first stage of the trial. We’ve reached this goal two months ahead of schedule, thanks to an incredible response from the MS community and the hard work of our Octopus trial sites.

Myelin repair trial completes recruitment – results expected late 2025

The 70th person with MS has joined our phase 2 myelin repair trial in Cambridge. The trial team have now reached their recruitment goal and we should have results next year.

New study suggests Black and South Asian people with MS in the UK don’t have a higher risk of severe MS

Dr Ben Jacobs is a neurologist and researcher, trying to get a better understanding of MS in people from non-European ancestries. He shares the results of his latest study.

Research shows genetically engineered human cells can repair myelin in mice

Scientists at our Edinburgh Centre for MS Research have used a gene-editing technique to boost myelin repair.

MS-STAT2 trial shows that simvastatin is not an effective treatment for secondary progressive MS

The results of the MS-STAT2 trial were announced by Professor Jeremy Chataway.

HERCULES trial shows tolebrutinib slows progression in non-active secondary progressive MS

For the first time, a phase 3 trial has shown a drug can slow down disability progression in people with secondary progressive MS who don’t have relapses. In two other phase 3 trials, tolebrutinib also slowed progression in relapsing MS.

New research suggests inflammation outside the brain contributes to MS progression

Research we funded found inflammation outside of the brain, which can be caused by factors like infections, smoking and obesity, could contribute to progression of MS.

Training the next generation of MS symptom management researchers

Researchers at our new Doctoral Training Centres will investigate how to best manage MS symptoms without using drugs.

Research shows diet has potential to help people with MS

New research combines evidence from around the world about which foods have the most potential to improve quality of life and reduce disability for people with MS.

New research reveals the power of microglia in smouldering MS

The brain’s resident immune cells are in overdrive in MS. New research has identified one potential reason why. And, how the cells could be controlled.

New genetics research could help diagnose MS earlier

Researchers have developed a way to predict whether people with optic neuritis will go on to be diagnosed with MS.

New insights into risk of MS in people living with HIV

A study of health information from people who are living with HIV and taking antiviral treatments showed they had a reduced risk of developing MS.

New research with ancient human DNA shows the origins of MS risk genes

An international collaboration of researchers has shown genes linked to MS may have evolved as a way to protect against infections.

Phase 3 trials show evobrutinib is no better than existing treatments for people with relapsing MS

Pharmaceutical company Merck announced the results of the EVOLUTION (evolutionRMS1 and evolutionRMS2) clinical trials earlier this month. They found evobrutinib wasn’t more effective at reducing relapses than existing drug teriflunomide.

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