Investigating the importance of Natural Killer cells in MS

Image shows a virus

Professor Daniel Altmann

Imperial College London


About the project

The immune attack on myelin in MS was previously thought to be caused by only one class of immune cell. However, there is growing evidence that a wider range of immune cells, including a class called Natural Killer cells, could also be involved.

Researchers will investigate whether the levels of Natural Killer cells are different between people with and without MS. They will look at different groups of Natural Killer cells, how they differ and how they interact with proteins and other cells in the body. The researchers will also look further into previous findings showing that levels of Natural Killer cells are reduced in people who are taking Tysabri.

How will it help people with MS?

Understanding the immune system and its role in MS is a key part of planning future treatment strategies for people living with the condition. We need to see the full picture of how these cells relate to MS so that new ways to treat the condition more effectively can be identified.

The difference you can make

Help us to support more projects like this, which explore the cause of MS and provide insights into possible new treatments.

The next research breakthrough is in reach

Your donation will help stop MS.

  • Please enter an amount

    Our minimum donation is £2, please enter a different amount.

£30could process one blood sample, giving researchers crucial information about genes and the immune system.

£50could pay for an hour on a microscope, so scientists can study cells and tissue in greater detail and improve their understanding of the biology of MS.

£100could pay for half an hour of MRI use, so researchers can monitor the success of clinical trials and understand MS in more detail.

Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.

  • Please enter an amount

    Our minimum donation is £2, please enter a different amount.

£10a month could pay for lab equipment like microscope slides to study the building blocks of MS

£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics

£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks

Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.

MS researcher at work in lab, using a pipette