Does early treatment with fingolimod or natalizumab improve the prognosis for people with multiple sclerosis?

Image shows a black and white clock tower

Tomas Kalincik

Neuroscience Foundation, Royal Melbourne Hospital

£72,338

About the project

We have 12 disease modifying therapies (DMTS) available for relapsing MS and each has its own risks and benefits. The more aggressive treatments, like Tysabri and Lemtrada are generally more effective than other therapies - but they are also more expensive and can have more dangerous side effects. There is an ongoing debate about how aggressively we should treat MS. Some neurologists believe that treating early with the most aggressive DMT is the best way, whereas other believe that aggressive therapies should only be used after the less effective (and safer) DMTs have failed. Our researchers aim to determine the long-term benefits of taking an aggressive DMT early using data from a global database called MSBase.

How will it help people with MS?

This research could influence clinical practice and access to aggressive DMTs globally, enabling people with MS make more informed decisions about their treatment following diagnosis.

The difference you can make

The sooner someone has access to a DMT following diagnosis, the more effective it can be long term for their condition. Help us find the most effective treatment timeline by donating today and supporting research projects like this.

Make a donation to help stop MS

The next research breakthrough is in reach. Your donation will help stop MS.

  • Please enter an amount

£10could buy vital lab supplies for MS researchers, helping them find ways to stop MS faster

£20could pay for lab equipment like petri dishes to grow bacteria important for studying the genetics of MS

£30could process one blood sample, giving us crucial information about genes that could lead to treatment breakthroughs

Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.

  • Please enter an amount

£10a month could pay for lab equipment like microscope slides to study the building blocks of MS

£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics

£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks

Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.

Young girl in hospital ward talking to male nurse