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MS Society Cambridge Centre for Myelin Repair

Glass media bottles
Lead researcher:
Professor Robin Franklin
Based at:
University of Cambridge
MS Society funding:
£1,641,443
Status:

About the project

We set up our Cambridge Centre in 2005, with the aim of developing treatments that promote myelin repair for people with MS.

Since it opened our Cambridge Centre has created a world-class research environment involving researchers from all around the UK – most notably at the MS Society Edinburgh Centre for MS Research.

Scientists at both centres have worked together to show that a molecule called RXR-gamma could encourage the brain’s own stem cells to repair myelin in animal models of MS. Researchers are now testing the benefits of a drug that targets RXR-gamma, called bexarotene, in a phase 2 clinical trial.

We announced four more years of funding for the MS Society Cambridge Centre for Myelin Repair in 2016. Researchers will continue to investigate the fundamental mechanisms behind myelin repair, with the hope of developing new treatments.

They will focus on understanding more about the cells capable of repairing myelin, and the impact ageing and lifestyle factors (such as diet and exercise) can have on these cells.

How will it help people with MS?

Scientists at our Cambridge Centre are working to identify and develop treatments for progressive MS. By working together, findings in the laboratory are being translated into trials to identify safe and effective treatments as quickly as possible.

We need treatments that repair myelin in order to enhance recovery, protect nerve cells from damage and ultimately slow or stop the progression of MS.

The difference you can make

Researchers at the MS Society Cambridge Centre for Myelin Repair are leading the way in developing treatments that promote myelin repair for people with MS. We are grateful to our supporters who have made this work possible.

Urgent appeal: Help us be there for everyone with MS

Urgent appeal: Help us be there for everyone with MS

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