MS Society Cambridge Centre for Myelin Repair

Professor Robin Franklin

University of Cambridge

£1,641,443

About the project

We set up the Cambridge Centre for Myelin Repair in 2005, with the aim of developing treatments that promote myelin repair for people with MS.

Since it opened the Cambridge Centre has created a world-class research environment involving researchers from all around the UK – most notably at our Edinburgh Centre for MS Research.

Scientists at both centres have worked together to show that a molecule called RXR-gamma could encourage the brain’s own stem cells to repair myelin in animal models of MS. Researchers will now test the benefits of a drug that targets RXR-gamma, called bexarotene, in a phase 2 clinical trial.

We announced four more years of funding for the Cambridge Centre in 2016. Researchers will continue to investigate the fundamental mechanisms behind myelin repair, with the hope of developing new treatments.

They will focus on understanding more about the cells capable of repairing myelin, and the impact ageing and lifestyle factors (such as diet and exercise) can have on these cells.

How will it help people with MS?

Scientists at the Cambridge Centre are working to identify and develop treatments for progressive MS. By working together, findings in the laboratory are being translated into trials to identify safe and effective treatments as quickly as possible.

We need treatments that repair myelin in order to enhance recovery, protect nerve cells from damage and ultimately slow or stop the progression of MS.

The difference you can make

Researchers at the Cambridge Centre for Myelin Repair are leading the way in developing treatments that promote myelin repair for people with MS. We are grateful to our supporters who have made this work possible.

>> Donate today to help us continue these vital research efforts.

The next research breakthrough is within reach

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