Using a new type of scanner to detect early MS progression
Biomarkers are detectable changes in the body. They can be anything from molecules in our blood to visible physical changes. We can use these biomarkers when we diagnose and track MS. But currently there are no good ways to detect early stages of MS progression.
Researchers now want to investigate if a new scanning technology called OPM-MEG can detect these early subtle changes in MS in real time. The OPM-MEG is a wearable device like a helmet, which means it can be worn whilst moving.
About the project
The researchers will scan three groups of people with the OPM-MEG scanner:
- People with progressive MS
- People with stable MS
- People without MS
Each person will complete three scans: one at the start of the study, another after six months, and a final scan after one year.
The researchers will then analyse how the biomarkers detected with the OPM-MEG change over time. And if these biomarkers worsen in people with progressive MS, and remain the same in people with stable MS.
How will it help people with MS?
Biomarkers can be used to diagnose, track and predict the course of a condition. Having new biomarkers for MS using the OPM-MEG could help us distinguish between silently progressing MS and stable MS.
These biomarkers could then be used to test how well treatments work in clinical trials. And they could help provide more certainty for people living with MS about the future.