Christina Applegate's MS misdiagnosis
This week, actress Christina Applegate announced on her podcast MeSsy that she had been misdiagnosed with MS.
Christina Applegate was diagnosed with multiple sclerosis in 2021. But after years of thinking she had the condition, her health team recently concluded her symptoms are not caused by MS.
After so many years living with what was thought to be multiple sclerosis (MS), it's understandable that Christina Applegate is shocked to hear she does not in fact have the condition.
How common is MS misdiagnosis?
MS is different for everyone and the symptoms can vary from person to person. A diagnosis can involve gathering evidence from MRI scans, lumbar punctures, and neurological examination, but there is no one test for it.
Other conditions can sometimes be mistaken for MS and it is a complex condition. There are no clear figures for how common misdiagnosis is, and it could vary from country to country and between hospitals. Studies tend to suggest rates of misdiagnosis can be between 5% and 15%. One 2019 study showed almost 20%. That study looked at diagnosis in two American hospitals.
Update to MS diagnostic criteria
In 2024 the McDonald Diagnostic Criteria, used by neurologists to diagnose MS, were updated based on the latest research available. This criteria aims to make MS diagnosis quicker and more accurate and reduce the risk of misdiagnosis. And because they are reviewed periodically by an international panel of experts, they reflect our latest understanding of the condition.
The difference a formal diagnosis of MS can make
We know having a formal diagnosis makes an important difference to people with MS symptoms, meaning they can access appropriate treatment and support.
We commend Christina Applegate for being so open about her experience over the last five years. While her symptoms turned out not to be caused by MS, we're sure sharing her story has helped raise awareness of a much misunderstood condition.
We know MS can be tough whatever stage you’re at. We’re here for everyone affected by MS and would urge anyone who needs more information or confidential advice to visit our MS Help Hub.
You can listen to Christina's podcast episode 'It's ok not to be ok' on her MeSsy podcast website.
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