How do mesenchymal stem cells from people with secondary progressive MS differ?
Professor Cris Constantinescu
University of Nottingham
About the project
The aim of this three-year project is to increase our knowledge about a type of stem cell called mesenchymal stem cells.
These particular stem cells are thought to have the ability to modulate the immune system as well as repair and limit damage to nerve fibres of the brain and spinal cord in people with MS.
In order to better understand the effect they might have, mesenchymal stem cells from people with secondary progressive MS will be compared with cells from people without MS in this study using a range of techniques.
How will it help people with MS?
Experts believe that transplantation of mesenchymal stem cells could be a good potential therapy for the treatment of secondary progressive MS and that their effectiveness should be tested in a clinical trial.
A greater understanding of mesenchymal stem cells will be valuable for the design of clinical trials to test these stem cells as a potential therapy for secondary progressive MS.
The difference you can make
There are currently no treatments available to help repair damage caused by MS. This type of project is vital if treatments are to become reality.
This project is jointly funded by the UK Stem Cell Foundation.
The next research breakthrough is in reach
Your donation will help stop MS.
£30could process one blood sample, giving researchers crucial information about genes and the immune system.
£50could pay for an hour on a microscope, so scientists can study cells and tissue in greater detail and improve their understanding of the biology of MS.
£100could pay for half an hour of MRI use, so researchers can monitor the success of clinical trials and understand MS in more detail.
Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.
£10a month could pay for lab equipment like microscope slides to study the building blocks of MS
£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics
£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks
Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.