Are systematic infections linked to progression in MS?

Image of a virus under the microscope. The virus is blue and red and there is a yellow background.

Lead researcher: Dr Ian Galea

Based in: University of Southampton

Grant we awarded: £256,023

 

This project aims to determine whether systemic infections (like colds, sinusitis and chest infections) affect disability in people with MS.

There is some evidence infections can cause degeneration of nerve cells in animal models of MS. There is also anecdotal evidence infections are associated with a more rapid worsening of disability in people with MS.

What happens in this project?

Researchers will monitor 50 people with MS for 2.5 years. During that time they'll record the number of infections people have and their response to each infection by collecting and analysing urine samples. They will also study the progression of MS using clinical exams and questions, along with MRI at the start and end of the study.

How will it help people with MS?

There is currently little understanding of the underlying factors involved in the accumulation of disability in people with MS. This study aims to further this understanding, by determining whether infections can cause disability in MS. If researchers can identify underlying factors, like infections, they may be able to develop strategies to slow, or even prevent disability accumulation in people with MS.

The difference you can make

We need to fund research into understanding why disability gradually worsens in people with MS, so that researchers can find ways to stop it. You can help by donating to stop MS today.

The next research breakthrough is in reach

Your donation will help stop MS.

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£10could buy vital lab supplies for MS researchers, helping them find ways to stop MS faster

£20could pay for lab equipment like petri dishes to grow bacteria important for studying the genetics of MS

£30could process one blood sample, giving us crucial information about genes that could lead to treatment breakthroughs

Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.

  • Please enter an amount

    Our minimum donation is £2, please enter a different amount.

£10a month could pay for lab equipment like microscope slides to study the building blocks of MS

£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics

£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks

Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.

Photo: young girl with MS sits in hospital chair smiling at male nurse