Measuring fatigue in MS
Lead researcher: Dr Jacqueline Palace
Based at: University of Oxford
MS Society funding: £40,000
About the project
About three quarters of people with MS experience fatigue as a symptom. For many it has a big impact on their quality of life. Currently, there's no way to precisely measure fatigue, making it hard to accurately test which treatments for it can make a real difference. This project will use functional magnetic resonance imaging (fMRI) to look for biological markers of fatigue. By measuring blood flow to the spine and brain researchers hope to identify the pathways in the brain that are activated in fatigue.
This will allow them to find objective measures of fatigue that can be used to assess different rehabilitation and treatment options in clinical trials and beyond.
How will it help people with MS?
Finding treatments that are effective for fatigue for people with MS is one of our top research priorities. To achieve this, it’s important to develop non-invasive techniques that accurately and objectively measure fatigue. We can then test and compare new treatments and therapies and pick the best. This project aims to deliver such a technique, as well as give us more insight into what happens in the brain during fatigue.
The difference you can makeWe want everyone with MS to have access to the treatments they need to live well with MS. With your help, we can continue to support vital research like this.
The next research breakthrough is in reach
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£30could process one blood sample, giving researchers crucial information about genes and the immune system.
£50could pay for an hour on a microscope, so scientists can study cells and tissue in greater detail and improve their understanding of the biology of MS.
£100could pay for half an hour of MRI use, so researchers can monitor the success of clinical trials and understand MS in more detail.
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