Does early treatment with Lemtrada or Tysabri improve prognosis for people with MS?

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Professor Neil Robertson

Cardiff University


About the project

We have 12 disease modifying therapies (DMTS) available for relapsing MS, which each have their own risks and benefits. The more aggressive treatments, like Tysabri and Lemtrada are generally more effective than other therapies, but they are also more expensive and associated with more dangerous side effects.

There is an ongoing debate about how aggressively we should treat MS. Some neurologists believe that treating early with the most aggressive DMT is the best way, whereas other believe that aggressive therapies should only be used after the less effective (and safer) DMTs have failed.

Our researchers aim to determine the long term benefits of taking an aggressive DMT early. They will measure how long it takes people on Tysabri or Lemtrada to progess compared with those taking less agressive DMTs and those who are not on any treatment.

How will it help people with MS?

This research could influence how doctors prescribe DMTs around the world and enable people with MS to make a more informed decision about treatments.

The difference you can make

The sooner someone has access to a DMT following diagnosis, the more effective it can be long term for their condition. Help us find the most effective treatment timeline by donating today and supporting research projects like this.

The next research breakthrough is in reach

Your donation will help stop MS.

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£30could process one blood sample, giving researchers crucial information about genes and the immune system.

£50could pay for an hour on a microscope, so scientists can study cells and tissue in greater detail and improve their understanding of the biology of MS.

£100could pay for half an hour of MRI use, so researchers can monitor the success of clinical trials and understand MS in more detail.

Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.

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£10a month could pay for lab equipment like microscope slides to study the building blocks of MS

£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics

£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks

Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.

MS researcher at work in lab, using a pipette