Could modified heparin promote myelin repair?
Professor Sue Barnett
University of Glasgow
About the project
In MS the protective myelin coating around nerve cells is damaged. Our bodies have the ability to repair myelin, but unfortunately in MS this process becomes less effective over time.
Researchers have discovered that myelin repair can be boosted in the lab using a modified version of the blood thinning drug heparin. It could also help to protect nerves from damage.
Our scientists will investigate the potential benefits of modified heparin in animal model of MS. They also compare the benefits of giving the drug orally or as an injection.
How will it help people with MS?
If modified heparin can myelin repair and protect nerves from damage in mice then it can be tested as a treatment for all forms of MS.
Because other forms of heparin have safely been used as medicines for many years it could go through clinical trials more quickly than other drugs.
The difference you can make
There are currently no treatments available to help repair damage caused by MS. We need to support innovative research like this if treatments are to be reality.
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