Can Gas6 help repair myelin in MS?

Photo of Dr Sassan Hafizi

Lead researcher: Dr Sassan Hafizi

Based at: University of Portsmouth

Grant we awarded: £177,930

In MS the immune system damages the protective myelin coating that surrounds nerves.

At first the body is capable of repairing myelin. But as MS progresses myelin repair becomes less effective and damage accumulates, which means that nerves can’t function properly.

What happens in the project?

 

Our researchers have identified a molecule called Gas6 that can help to reduce myelin damage. They will now investigate how Gas6 works in more detail using mice with a condition similar to MS. They will also explore how we can target Gas6 to boost the natural myelin repair process in the brain.

How will it help people with MS?

We need to know how Gas6 works to help us develop new treatments that repair myelin. These treatments have the potential to slow or stop all types of MS.

The difference you can make

There are currently no treatments available to help repair damage caused by MS. We need to support innovative projects like these if treatments are to become a reality.

The next research breakthrough is in reach

Your donation will help stop MS.

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£30could process one blood sample, giving researchers crucial information about genes and the immune system.

£50could pay for an hour on a microscope, so scientists can study cells and tissue in greater detail and improve their understanding of the biology of MS.

£100could pay for half an hour of MRI use, so researchers can monitor the success of clinical trials and understand MS in more detail.

Every penny you give really does take us a step closer to stopping MS. Your donation will make a difference.

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£10a month could pay for lab equipment like microscope slides to study the building blocks of MS

£20a month could pay for lab equipment like petri dishes to grow bacteria important for studying genetics

£30a month could process a blood sample to help us understand what causes MS, so we can stop it in its tracks

Your regular donation means we can keep funding world class MS research with confidence. Together we will stop MS.

MS researcher at work in lab, using a pipette