Potential way to repair myelin discovered by MS Society researchers

Published date: 21 Jul 2013 at 5:01PM

Researchers based at the Edinburgh Centre for Translational Research and Cambridge Centre for Myelin Repair have found that a protein inside cells, known as ‘activin-A’, could be targeted as a way to repair damage to myelin.

The researchers studied laboratory models of demyelination to try and discover more about how remyelination happens.

They found that if activin-A production was blocked, it stopped oligodendrocytes (myelin-making cells) producing the myelin that is needed to repair the damaged sheath.

Researchers will now look to find a treatment that stimulates activin-A – so that it encourages the repair of myelin in the body.

The research was published this week in Nature Neuroscience.

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Page last updated: 22 Jul 2013
We urgently need therapies that can help slow the progression of MS and so we’re delighted researchers have identified a new potential way to repair damage to myelin. We look forward to seeing this research develop further.
Dr Susan Kohlhaas, Head of Biomedical Research at the MS Society

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