Stop MS Appeal

To stop MS, we need to find treatments that slow or stop progression for everyone. That's why research is so important. Find out how your support helps research and clinical trials.

Over 150,000 people live with multiple sclerosis (MS) in the UK. It’s different and unpredictable for everyone, making it hard to know how it’ll progress. At the moment, existing drugs only work on one aspect of MS - the immune system.

To stop MS, we also need to find ways to repair myelin, the protective coating around nerves, damaged in MS. To do this, we need to connect research from the lab right through to the clinic. We need to understand things like how damaged nerves signal for help and how myelin-making cells are activated.

With your help, we’re funding pioneering research like Professor Klaus Schmierer’s. He’s lead researcher in ChariotMS, a trial that’s in phase 2 of testing. It’s looking to see if a drug called cladribine (brand name Mavenclad) can help people with advanced progressive MS maintain the use of their arms and hands.

Together, researchers, volunteers taking part in studies and everyone helping raise funds will make history.

Meet the history makers