The Plan
The research programme can be divided into three phases; understand, test and then trial.
The Cambridge team feel that phases 1 and 2 will be significantly advanced within 5 years and that within 10 years, they could be trialling a treatment.
Understand: how remyelination works
- Identify the factors that allow stem cells to carry out myelin repair - these factors may be used to promote repair
- Reveal how nerve cells respond to loss
Charles ffrench-Constant | James Fawcett | Robin Franklin | Siddharthan Chandran | Maria Grazia Spillantini
Test: new therapies in experimental models
- Test restoration of myelin – to give insight into how to protect nerves
- Test the ability of stem cells to protect demyelinated axons – this might be by production of new myelin, or protective substances
Robin Franklin |William Blakemore
Trial: new therapies with people with MS
- Trial in people with MS - to check effectiveness
Alasdair Coles | Alastair Compston | Siddharthan Chandran
