Fatigue
Fatigue - an overwhelming tiredness - is one of the most common invisible symptoms of MS.
Some people find it's the symptom that affects them most. But there are ways to manage it and minimise its effects on your life.
What causes MS fatigue?
Different factors can cause fatigue when you have MS. We separate them into primary fatigue and secondary fatigue.
- Primary fatigue is caused by MS damage in the brain and spinal cord. And lots of processes might be involved. One idea from researchers is that passing messages around nerve damage takes extra energy.
- Secondary fatigue is caused by living with MS symptoms like pain, or disturbed sleep.
Last full review: 1 December 2025
Next review date: 1 December 2028
We also update when we know about important changes.
In this section
For me, fatigue feels like I'm swimming in thick chocolate (I can dream!) and usually I can't carry on. But I've learnt not to put pressure on myself. I can only do my best.
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Helpful resources
From symptoms and treatments to accessing care and support, our booklets and factsheets are packed full of information and tips on living well with MS.
You can download them from our website or order copies from our online shop.
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