How are steroids administered?

Courses of steroids are either intravenous (administered into the vein) or oral (in tablet form). Intravenous steroid treatment is usually given during a stay in hospital, but can sometimes be administered at home, which many people prefer. Oral steroids can be taken at home. Whichever is used, NICE recommend the following courses:

• Intravenous methylprednisolone, 500 – 1,000mg daily, for three to five days
• High-dose oral methylprednisolone, 500 – 2,000mg daily, for three to five days

What are the side effects of steroids?

All drugs have unwanted effects. During an infusion of steroids, some people experience a metallic taste in the mouth. Occasionally, if the needle has been inserted incorrectly, the injection site swells and becomes painful. Increased heart rate, hot flushes or a red face may also recur. There can also be problems sleeping and an increased need to urinate, particularly at night.

Taking steroids can also affect people’s moods. Some people can experience a sense of euphoria that causes them to think there is an actual improvement in their MS.

There is also concern over prescribing steroids because of fears about storing up problems for the future, but longterm side effects of steroids, which can include diabetes and osteoporosis, ought not to be an issue unless the person with MS is taking steroids excessively. Doctors can monitor your risk of osteoporosis and they may prescribe supplements to guard against it, if necessary.